1/28/2024 0 Comments Presenting ivcd dataWritten informed consent was obtained from each patient early on during this study however, the IRBs of each hospital waived the requirement for informed consent, as this study presented minimal risk for the patients and was initiated and sponsored by the Korean Ministry of Health and Welfare to improve public health. The study protocol was approved by the Ethics Committee/Institutional Review Board (IRB) at each hospital. 10), 11) Among the patients enrolled in the KorAHF registry, patients who met the following criteria were included in this analysis: 1) patients who were initially diagnosed with CS and 2) were able to undergo baseline electrocardiography. Detailed information of the study design and its results have been previously reported. Demographic characteristics, comorbidities, clinical presentation, medical history, laboratory tests, electrocardiographic findings, transthoracic echocardiographic findings, additional treatments, and outcome data were collected at admission and during the follow-up period. Patients hospitalized for acute HF from 10 tertiary university hospitals throughout the country were enrolled from March 2011 to February 2014 ( NCT01389843). The study population was selected from The Korean Acute Heart Failure (KorAHF) registry, a prospective multicenter cohort study. We hypothesized that patients with prolonged QRS duration could represent a high-risk phenotype within the CS spectrum. The present study aimed to evaluate the prognostic implications of QRS duration and associated factors in a large cohort of acute HF patients with CS. However, the prognostic implications of QRS duration have not been clearly defined in the context of acute HF. 8) A wide QRS complex reflecting left-sided intraventricular conduction delay in patients with chronic HF is associated with more advanced myocardial disease, worse left ventricular (LV) function, poorer prognosis, and a higher all-cause mortality rate compared with patients with a narrow QRS complex. Prolonged QRS duration means electrical and mechanical dyssynchrony in the diseased heart. 4), 5), 6), 7) In this regard, early identification of risk factors associated with CS in HF may prove particularly helpful when considering therapeutic options. Previous studies have shown that in-hospital mortality increases to 40–50% when CS develops in HF patients. 1), 2), 3) CS has many causes, including acute coronary syndrome (ACS), heart failure (HF), and valvular heart disease, and it is one of the most serious complications of these conditions. Jung Ae Hong, MD, 1 Min-Seok Kim, MD, PhD, 1 Hanbit Park, MD, 1 Sang Eun Lee, MD, 1 Hae-Young Lee, MD, 2 Hyun-Jai Cho, MD, 2 Jin Oh Choi, MD, 3 Eun-Seok Jeon, MD, 3 Kyung-Kuk Hwang, MD, 4 Shung Chull Chae, MD, 5 Sang Hong Baek, MD, 6 Seok-Min Kang, MD, 7 Dong-Ju Choi, MD, 8 Byung-Su Yoo, MD, 9 Kye Hun Kim, MD, 10 Myeong-Chan Cho, MD, 5 Jae-Joong Kim, MD, 1ġDepartment of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ĢDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ģDepartment of Internal Medicine, Sungkyunkwan University College of Medicine, Seoul, Korea.ĤDepartment of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.ĥDepartment of Internal Medicine, Kyungpook National University College of Medicine, Daegu, Korea.ĦDepartment of Internal Medicine, The Catholic University of Korea, Seoul, Korea.ħDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ĨDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ĩDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.ġ0Heart Research Center of Chonnam National University, Gwangju, Korea.ġ1Division of Cardiology, Cardiovascular Center, Mediplex Sejong Hospital, Incheon, Korea.Ĭardiogenic shock (CS) is generally defined as a systolic blood pressure (SBP) <90 mmHg and clinical or laboratory signs of tissue hypoperfusion despite adequate volume status. Prognostic Value of QRS Duration among Patients with Cardiogenic Shock Complicating Acute Heart Failure: Data from the Korean Acute Heart Failure (KorAHF) Registry
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